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Profertil (Brand name: Clomid)
- $0.44
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
30 pills | $1.39 | $41.59 | ||
60 pills | $1.02 | $21.77 | $83.17 $61.40 | |
90 pills | $0.90 | $43.55 | $124.76 $81.21 | |
120 pills | $0.84 | $65.33 | $166.34 $101.02 | |
180 pills | $0.78 | $108.88 | $249.52 $140.63 | |
270 pills | $0.74 | $174.20 | $374.27 $200.07 | |
360 pills | $0.72 | $239.54 | $499.03 $259.49 |
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
30 pills | $1.17 | $35.09 | ||
60 pills | $0.86 | $18.37 | $70.18 $51.80 | |
90 pills | $0.76 | $36.75 | $105.26 $68.52 | |
120 pills | $0.71 | $55.12 | $140.35 $85.24 | |
180 pills | $0.66 | $91.85 | $210.53 $118.67 | |
270 pills | $0.63 | $146.99 | $315.79 $168.80 | |
360 pills | $0.61 | $202.10 | $421.06 $218.95 |
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
60 pills | $0.58 | $34.63 | ||
90 pills | $0.52 | $4.99 | $51.94 $46.95 | |
120 pills | $0.49 | $9.97 | $69.25 $59.28 | |
180 pills | $0.47 | $19.94 | $103.88 $83.93 | |
270 pills | $0.45 | $34.91 | $155.82 $120.91 | |
360 pills | $0.44 | $49.86 | $207.76 $157.90 |
Common use
Profertil is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins (prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone), stimulates ovulation; in large doses slows secretion of gonadotropins. Profertil stimulates ovulation and prepares the body for pregnancy. This medication may be used for male patients with infertility caused by low production of sperm.
Dosage and direction
Profertil is administered to stimulate ovulation. It is recommended to start with 50 mg 1 time a day at bedtime, starting from 5th day of the menstrual cycle during 5 days (in the absence of the cycle - at any time). In case of no effect (ovulation does not occur within 30 days) increase the dose to 150 mg / day or lengthen the course to 10 days. Take exactly as prescribed, do not take the medication in larger quantities.
Precautions
Before taking Profertil notify your doctor if you have ever had any allergic reaction to clomiphene, liver diseases, mental depression, thrombophlebitis. This drug may cause vision problems, dizziness, or lightheadedness, be especially attentive if you need driving or operating machinery which requires high concentration of attention.
Contraindications
Hypersensitivity, liver or kidney failure, metrorrhagia of unknown etiology, ovarian cysts, neoplasms of genital organs, tumor or hypofunction of the hypophysis, endometriosis, ovarian failure together with hyperprolactinaemia, pregnancy.
Possible side effect
Together with allergy symptoms such as swelling of lips, tongue, or face or hives in some patients may appear the following conditions: ovarian enlargement presenting as abdominal or pelvic pain, flushing, nausea, vomiting, or diarrhea, blurred vision, headache, abnormal uterine bleeding.
Drug interaction
Inform your doctor and laboratory operators about all medications and herbal products you are taking if you are treated with Profertil.
Missed dose
If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake according to your schedule. If so skip the missed dose. Do not try to make up a missed dose by taking an extra one.
Overdose
If you suspect that you took too much of the medication seek for immediate medical attention.
Storage
Store Profertil in a dry place away from sunlight at room temperature between 15-30 C (59-86 F).
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Type | Small Molecule |
Accession Number | DB00882 (APRD00880) |
Groups | Approved, Investigational |
Synonyms |
|
UNII | 1HRS458QU2 |
CAS number | 911-45-5 |
Weight | Average: 405.96 Monoisotopic: 405.18594223 |
Chemical Formula | C26H28ClNO |
InChI | InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3 |
IUPAC Name | {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine |
Protein binding | Not Available |
Toxicity | The acute oral LD50 of clomifene is 1700 mg/kg in mice and 5750 mg/kg in rats. The toxic dose in humans is not known. Toxic effects accompanying acute overdosage of clomifene have not been reported. Signs and symptoms of overdosage as a result of the use of more than the recommended dose during clomifene therapy include nausea, vomiting, vasomotor flushes, visual blurring, spots or flashes, scotomata, ovarian enlargement with pelvic or abdominal pain. |
Half life | 5-7 days |
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