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PMS-Valsartan (Brand name: Diovan)

  • $0.91
  • Brand name: Diovan
  • Availability: In Stock
  • Active Ingredient Valsartan
PMS-Valsartan is an angiotensin receptor blocker, it relaxes blood vessels and has a hypotension effect.
Other names of PMS-Valsartan (Brand name: Diovan): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Arovan   Alsartan   Alsart   Alpertan   Acavexal   Adwivalsar   Alencal/Vals   Alkapress Plus   Alpertan   Alpertan D   Alsarkare   Alsart   Alsartir   Alvastran   Alvastran HCT   Amlodipin Valsartan HCT Sandoz   Amlodipin Valsartan Sandoz   Amlopres-VL   Amlosartan   Amlovaltan   Amlovan   Amplex   Ampliron   Ampliron VL   Amval   Apo-Valsart   Apo-Valsart HCT   Apo-Valsartan   Apo-Valsartan/HCTZ   Aralter   Aralter Plus   Arbiten   Arbiten Plus   Arb-XG   Arovan   Artinova   Atedio   Atenzio   Atenzio Plus   Avalsan   Avan   Avan HTC   Avasart   Avasart HCT   Avassan   Awalten   Axudan   PMS-Valsartan  
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40 mg
Product name Per Pill Per Pack  
30 pills $1.23 $37.04
60 pills $1.06 $74.08 $63.45
90 pills $1.00 $111.11 $89.87
120 pills $0.97 $148.15 $116.28
180 pills $0.94 $222.23 $169.09
270 pills $0.92 $333.34 $248.35
360 pills $0.91 $444.46 $327.56
160 mg
Product name Per Pill Per Pack  
30 pills $2.49 $74.78
60 pills $1.89 $149.57 $113.67
90 pills $1.70 $224.35 $152.56
120 pills $1.60 $299.14 $191.45
180 pills $1.50 $448.70 $269.23
270 pills $1.43 $673.06 $385.88
360 pills $1.40 $897.41 $502.56
80 mg
Product name Per Pill Per Pack  
30 pills $1.85 $55.45
60 pills $1.55 $110.90 $93.17
90 pills $1.45 $166.35 $130.91
120 pills $1.41 $221.80 $168.62
180 pills $1.36 $332.69 $244.08
270 pills $1.32 $499.04 $357.26
360 pills $1.31 $665.39 $470.45

Common use

This medication is a peripheral vasodilatator with a hypotension effect. It specifically blocks angiotensin I receptors. Results of Valsartan activity may be observed in 2 hours after its intake, maximal effect is reached in 4-6 hours. Duration of its actions is over 24 hours. Valsartan is used to treat chronic heart failure (NYHA class III-IV). The medication in particular is prescribed after heart attacks.

Dosage and direction

Once a day together with food or before a meal. Maximal daily dose is 160 mg, usual dose is 80 mg daily. Depending on your condition dosage may change. Do not take this medication if it was not administered to you. Follow all directions of your doctor.

Precautions

FDA pregnancy category D. Valsartan may be harmful to an unborn baby. Continue treatment with this medication even if you feel fine unless your doctor told you different. In rare cases, Valsartan can cause a condition that results in the breakdown of skeletal muscle tissue, which then leads to kidney failure. In this case such symptoms as fever, nausea, dark colored urine, muscle pain appear and you should inform your doctor immediately about it to avoid further complications.

Contraindications

Hypersensitivity, pregnancy, breastfeeding. The medication should be administered cautiously in patients with a biliary cirrhosis, bile duct obstruction, kidney failure, stenosis of kidney artery.

Possible side effect

Headache, dizziness, asthenia, insomnia, diarrhea, abdominal pain, vomit, coughing, running nose,impotence, reduced renal function, and allergic reactions.

Drug interaction

Potassium-sparing diuretics, K+ medications, salts which contain K+ in interaction with Valsartan may facilitate development of hyperpotassemia. Diuretics in combination with Valsartan cause hypotention.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If it occured skip the missed dose. Do not try to compensate a missed dose by taking an extra one.

Overdose

If you suppose that you overdosed Valsartan seek for immediate medical attention. Symptoms of overdose may include dizziness, increased heart rate, increased levels of potassium in the blood, kidney failure, Loss of consciousness.

Storage

Store Valsartan at room temperature, 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Chills
  • fever
  • hoarseness
  • sore throat
  • swelling of the mouth, hands, or feet
  • trouble with swallowing or breathing (sudden)

Less Common

  • Bloody urine
  • cold sweats
  • confusion
  • decreased frequency or amount of urine
  • difficult breathing
  • dizziness, faintness, or lightheadedness when getting up from a lying position
  • fainting
  • increased thirst
  • irregular heartbeat
  • loss of appetite
  • lower back or side pain
  • nausea
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • swelling of the face, fingers, or lower legs
  • unusual tiredness or weakness
  • vomiting
  • weight gain
  • Abdominal or stomach pain
  • back pain
  • blurred vision
  • cold or flu-like symptoms
  • coughing
  • diarrhea
  • difficulty with moving
  • headache
  • muscle pain or stiffness
  • pain, swelling, or redness in the joints

Incidence Not Known

  • Dark urine
  • general tiredness and weakness
  • light-colored stools
  • upper right abdominal or stomach pain
  • yellow eyes and skin
  • Hair loss
  • thinning of the hair
Type Small Molecule
Accession Number DB00177  (APRD00133)
Groups Approved, Investigational
Synonyms
  • (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
  • N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
  • N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
UNII 80M03YXJ7I
CAS number 137862-53-4
Weight Average: 435.5188
Monoisotopic: 435.227039819
Chemical Formula C24H29N5O3
InChI
InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
IUPAC Name
(2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid
Protein binding

94 - 97% bound to serum proteins, primarily serum albumin

Toxicity Not Available
Half life

The initial phase t1/2 α is < 1 hour while the terminal phase t1/2 β is 5-9 hours.

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  • Tindouf
  • Tizi Ouzou