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Pms-sotalol (Brand name: Betapace)

  • $0.73
  • Brand name: Betapace
  • Availability: In Stock
  • Active Ingredient Sotalol
Pms-sotalol is used for treating certain types of irregular heartbeat (ventricular arrhythmias).
Other names of Pms-sotalol (Brand name: Betapace): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Pms-sotalol  
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40 mg
Product name Per Pill Per Pack  
30 pills $1.20 $36.02
60 pills $0.95 $72.05 $56.72
90 pills $0.86 $108.07 $77.42
120 pills $0.82 $144.10 $98.11
180 pills $0.78 $216.14 $139.52
270 pills $0.75 $324.22 $201.61
360 pills $0.73 $432.29 $263.70

INDICATIONS

Pms-sotalol is used for treating certain types of irregular heartbeat (ventricular arrhythmias). Pms-sotalol is a beta-blocker. It works by helping the heart beat regularly for a longer period of time.

INSTRUCTIONS 

Use Pms-sotalol as directed by your doctor.

  • Take Pms-sotalol by mouth with or without food. Try to take it the same way (either with food or without food) each time you take your dose. Check with your doctor or pharmacist if you have questions about taking Pms-sotalol with food.
  • Do not take an antacid that has aluminum or magnesium in it within 2 hours before or after you take Pms-sotalol.
  • Taking Pms-sotalol at the same time each day will help you remember to take it.
  • Continue to use Pms-sotalol even if you feel well. Do not miss any dose.
  • If you miss a dose of Pms-sotalol, skip the missed dose. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pms-sotalol.

STORAGE

Store Pms-sotalol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pms-sotalol out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Sotalol HCl.

SAFETY INFORMATION

Do NOT use Pms-sotalol if:

  • you are allergic to any ingredient in Pms-sotalol
  • you have certain heart problems (eg, severe low heart rate, uncontrolled heart failure, certain types of abnormal heartbeat rhythm), low blood potassium or magnesium levels, severe kidney problems, or a history of asthma
  • you are taking cisapride, astemizole, terfenadine, mibefradil, dofetilide, or a theophylline (eg, aminophylline).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Pms-sotalol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have breathing or lung problems (eg, chronic obstructive pulmonary disorder [COPD], asthma), a decreased appetite, an overactive thyroid, kidney problems, bronchitis, diabetes, blood flow problems, a tumor on your adrenal gland, or other heart problems
  • if you are scheduled for surgery.

Some medicines may interact with Pms-sotalol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Indomethacin or phenylpropanolamine because they may decrease Pms-sotalol's effectiveness
  • Clonidine, diltiazem, mibefradil, nifedipine, or verapamil because the risk of side effects, such as low blood pressure or heart problems, may be increased
  • Amiodarone, antiarrhythmics (eg, quinidine, propafenone), arsenic, cisapride , dofetilide, droperidol, H1 antagonists (eg, astemizole, terfenadine), ketanserin, macrolides and ketolides (eg, erythromycin, azithromycin), mefloquine, phosphodiesterase type 5 inhibitors (eg, sildenafil), phenothiazines (eg, thioridazine), quinolones (eg, ciprofloxacin), or ziprasidone because the risk of abnormal heart rhythms may be increased
  • Bupivacaine, cocaine, epinephrine, insulin, lidocaine, meglitinide antidiabetics (eg, nateglinide), nifedipine, or quinazolines (eg, prazosin) because the risk of their side effects may be increased by Pms-sotalol
  • Certain stimulants (eg, albuterol, pseudoephedrine), phenformin, or theophyllines (eg, aminophylline) because their effectiveness may be decreased by Pms-sotalol.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pms-sotalol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Pms-sotalol may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Pms-sotalol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Pms-sotalol may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Tell your doctor or dentist that you take Pms-sotalol before you receive any medical or dental care, emergency care, or surgery.
  • Do not suddenly stop taking Pms-sotalol. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Pms-sotalol. The risk may be greater if you have certain types of heart disease. Heart disease is common and you may not know you have it. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Pms-sotalol again.
  • Lab tests, including heart function, kidney function, and blood pressure monitoring, may be performed while you use Pms-sotalol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pms-sotalol while you are pregnant. Pms-sotalol is found in breast milk. Do not breastfeed while taking Pms-sotalol.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Dizziness; drowsiness; headache; light-headedness; tiredness; trouble sleeping.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormally fast, slow, or irregular heartbeat; changes in vision; decreased appetite; excessive thirst; numbness of an arm or leg; severe or persistent nausea, vomiting, or diarrhea; severe stomach pain; sharp or crushing chest pain; sudden leg pain; sudden severe headache, vomiting, dizziness, or fainting; sudden shortness of breath; unusual sweating.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Fast breathing
  • pinpoint red spots on the skin
  • Feeling of constant movement of self or surroundings
  • hair loss or thinning of the hair
  • itching skin
  • muscle aching or cramping
  • muscle pains or stiffness
  • quick to react or overreact emotionally
  • sensation of spinning
  • severe sunburn

More Common

  • Blurred vision
  • chest pain or discomfort
  • confusion
  • difficult or labored breathing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, slow, irregular, pounding, or racing heartbeat or pulse
  • lightheadedness, dizziness, or fainting
  • nausea and vomiting
  • sweating
  • swelling of the face, fingers, feet, or lower legs
  • tightness in the chest
  • unusual tiredness or weakness
  • Acid or sour stomach
  • difficulty with sleeping
  • heartburn or indigestion
  • pain in the arms or legs

Less Common

  • Abdominal or stomach pain or swelling
  • body aches or pain
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • cough or hoarseness
  • decreased alertness
  • difficulty with speaking
  • dilated neck veins
  • double vision
  • extreme fatigue
  • feeling of warmth or heat
  • fever or chills
  • flushing or redness of the skin, especially on the face and neck
  • headache
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • irregular breathing
  • joint pain or swelling
  • loss of voice
  • lower back or side pain
  • nervousness
  • noisy breathing
  • painful, burning, or difficult urination
  • pounding in the ears
  • slow speech
  • weight gain
  • Changes in vision
  • decreased sexual performance or desire
  • loss of appetite
  • mood changes
  • night blindness
  • passing gas
  • skin rash
  • weight changes
Type Small Molecule
Accession Number DB00489  (APRD01230)
Groups Approved
Synonyms
  • 4'-(1-Hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
  • Sotalol
  • Sotalolo
  • Sotalolum
UNII A6D97U294I
CAS number 3930-20-9
Weight Average: 272.364
Monoisotopic: 272.119463206
Chemical Formula C12H20N2O3S
InChI
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
IUPAC Name
N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide
Protein binding

Sotalol does not bind to plasma proteins.

Toxicity

The most common signs to be expected are bradycardia, congestive heart failure, hypotension, bronchospasm and hypoglycemia. In cases of massive intentional overdosage (2-16 grams) of sotalol the following clinical findings were seen: hypotension, bradycardia, cardiac asystole, prolongation of QT interval, Torsade de Pointes, ventricular tachy-cardia, and premature ventricular complexes.

Half life

Mean elimination half-life is 12 hours. Impaired renal function in geriatric patients can increase the terminal elimination half-life.

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Algeria, including the following:

  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
  • Tébessa
  • El Oued
  • Skikda
  • Tiaret
  • Béjaïa
  • Tlemcen
  • Ouargla
  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou