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Prilactone (Brand name: Aldactone)
Aporasnon Alspiron Almatol Alizar Alexan Aldozone Aldospirone Aldonar Aldoleo Aldazide Aldazida Aldactide Aldactazine Aldactazide Aldactacine Aldactacine Aldactazida Aldactazide Aldactazine Aldactide Aldactin Aldactone A Aldactone A 10% Aldactone-A Aldactone-D Aldactone-Saltucin forte Aldazida Aldazide Aldoleo Alspiron Altizide Spironolactone RPG Altone Aporasnon Prilactone
|Product name||Per Pill||Savings||Per Pack|
|60 pills||$0.99||$8.54||$68.10 $59.56|
|90 pills||$0.95||$17.08||$102.15 $85.07|
|120 pills||$0.92||$25.63||$136.20 $110.57|
|180 pills||$0.90||$42.71||$204.30 $161.59|
|270 pills||$0.88||$68.34||$306.45 $238.11|
|360 pills||$0.87||$93.96||$408.60 $314.64|
|Product name||Per Pill||Savings||Per Pack|
|60 pills||$1.10||$9.44||$75.24 $65.80|
|90 pills||$1.04||$18.88||$112.86 $93.98|
|120 pills||$1.02||$28.32||$150.48 $122.16|
|180 pills||$0.99||$47.20||$225.72 $178.52|
|270 pills||$0.97||$75.52||$338.58 $263.06|
|360 pills||$0.97||$103.82||$451.44 $347.62|
Magnium and potassium-sparing diuretic and aldosterone antagonist. It competitively associates with aldosterone receptors in in the distal parts of the nephron. It has a diuretic effect, increases excretion of natrium ions and decreases excretion of potassium and magnium, decreases urinary acidity. The diuretic effect of the medicine is moderate and appears usually after 2-5 days of treatment and continues during 2-3 days after discontinuance of the medicine intake. A weak hypotension effect appear usually in 2-3 weeks of treatment. Prilactone is used in combination with other drugs to treat hypertension. It also facilitates removal of excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease.
Dosage and direction
Daily dose for adults in arterial hypertension, edema syndrome is 50-100 mg for adults. It should be divided into 1-2 intakes a day. On necessity the dose maybe gradually increased up to 200 mg a day. Duration of treatment is not less than two weeks. For other conditions such as chronic congestive heart failure, cirrhosis, nephrotic syndrome and others different dosage maybe recommended. Consult your doctor before you decide to take this medicine. Prilactone should be taken after a meal and the most preferable is a single dose before bedtime.
Do not drink alcohol as it increases some of the side effects of Prilactone. Avoid eating too much salt because excess of salt may cause your body to retain water and effectiveness of Prilactone decreases. It is recommended not to take salt substitutes or low-sodium milk products which contain potassium. Avoid becoming overheated or dehydrated during exercising. Talk with your doctor about amount of liquids you should consume. Do not stop using this medicine even if you feel improvement of your health if you are being treated for high blood pressure.
Hypersensitivity, Addison disease, hypercaliemia, hyperpotassiemia, concomitant intake with potassium supplements or other potassium-sparing diuretics such as Aldactazide, amiloride (Midamor, Moduretic), triamterene (Dyrenium, Dyazide, Maxzide), hyponatriemia, chronic kidney failure, diabetic nephropathy, anuria, liver failure, diabetes at supposed chronic kidney failure, diabetic nephropathy, pregnancy, and some others. Please take this medicine only if it is advised by your doctor.
Possible side effect
Side effects of the medicine include headache, diarrhea, cramps, drowsiness, rash, nausea, vomiting, impotence, irregular menstrual periods, and irregular hair growth. Fluid and electrolytes imbalance are likely, so patients should be monitored carefully. Enlargement of the breasts may also occur depending on dose and duration of therapy. This condition is usually reversible when you discontinue to take Prilactone.
This medicine can lower blood sodium levels while raising blood potassium levels. Excessively high potassium levels in blood sometimes cause potentially life-threatening abnormalities in heart rhythm. Therefore, Prilactone usually is not administered with other agents that can raise blood potassium levels. Prilactone can cause elevation of blood digoxin (Lanoxin) to toxic levels.
Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.
Immediate medical attention in needed in case you overdosed intake of the medicine. Overdose symptoms may include drowsiness, confusion, red skin rash, nausea, vomiting, or diarrhea.
Prilactone should be stored at room temperature, below 25 C (77 F).
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:
Incidence Not Known
- Bleeding gums
- bloody or black, tarry stools
- bloody urine
- blurred vision
- breast pain
- chest pain
- clay-colored stools
- clear or bloody discharge from the nipple
- cloudy urine
- dark urine
- decrease in urine output or decrease in urine-concentrating ability
- difficulty with swallowing
- dimpling of the breast skin
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast or irregular heartbeat
- fever with or without chills
- general feeling of tiredness or weakness
- hives, itching, or skin rash
- increased thirst
- inverted nipple
- loss of appetite
- loss of consciousness
- lower back or side pain
- lump in the breast or under the arm
- muscle pain or cramps
- muscle spasms or twitching
- painful or difficult urination
- persistent crusting or scaling of the nipple
- pinpoint red spots on the skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness or swelling of the breast
- severe stomach pain
- shakiness and unsteady walk
- sore on the skin of the breast that does not heal
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- stomach cramping, burning, or tenderness
- swelling of the face, fingers, feet, ankles, or lower legs
- swollen, painful, or tender lymph glands in the neck, armpit, or groin
- tightness in the chest
- troubled breathing
- unpleasant breath odor
- unsteadiness, trembling, or other problems with muscle control or coordination
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood or material that looks like coffee grounds
- weight gain
- yellow eyes or skin
- Burning feeling in the chest or stomach
- decreased interest in sexual intercourse
- hair loss or thinning of the hair
- inability to have or keep an erection
- leg cramps
- loss in sexual ability, desire, drive, or performance
- pain in the nipples
- sores, welts, or blisters
- stomach upset
- swelling of the breasts or breast soreness in both females and males
- unusual dullness or feeling of sluggishness
|Accession Number||DB00421 (APRD01234)|
Spironolactone and its metabolites are more than 90% bound to plasma proteins.
The oral LD50 of spironolactone is greater than 1,000 mg/kg in mice, rats, and rabbits. Acute overdosage of spironolactone may be manifested by drowsiness, mental confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, or diarrhea. Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats.
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