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Pedrox (Brand name: Roxithromycin)
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Pedrox (Brand name: Roxithromycin)

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  • $0.78
  • Brand name: Roxithromycin
  • Availability: In Stock
  • Active Ingredient
Pedrox is used for treating several different infections, including some STDs, upper and lower respiratory tract infections and asthma, gum infections like gingivitis, and bacterial infections associated with stomach and intestinal ulcers.
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150 mg
Product name Per Pill Per Pack  
30 pills $1.26 $37.65
60 pills $1.00 $75.31 $59.70
90 pills $0.91 $112.96 $81.74
120 pills $0.86 $150.61 $103.79
180 pills $0.82 $225.92 $147.87
270 pills $0.79 $338.88 $214.00
360 pills $0.78 $451.84 $280.15

INDICATIONS

Pedrox is a macrolide antibiotic. Pedrox is very similar in composition, chemical structure (semi-synthetic) and mechanism of action to erythromycin, azithromycin, or clarithromycin. Antibiotics such as Pedrox can often be prescribed for several different infections, including some STDs, upper and lower respiratory tract infections and asthma, gum infections like gingivitis, and bacterial infections associated with stomach and intestinal ulcers. Pedrox is absorbed well into the gastro-intestinal tract, with few side effects, and actively responds to the presence of cryptosporidium, pneumocystis carinii (PCP), toxoplasma gondii, and Mycobacterium Avium (MAC).

INSTRUCTIONS 

Use Pedrox as directed by your doctor.

  • Take Pedrox by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • To clear up your infection completely, take Pedrox for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Pedrox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pedrox.

STORAGE

 Store Pedrox at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pedrox out of the reach of children and away from pets.

SAFETY INFORMATION

Do NOT use Pedrox if:

  • you are allergic to any ingredient in Pedrox.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Pedrox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances.

Ask your health care provider if Pedrox may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Pedrox for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Pedrox only works against bacteria; it does not treat viral infections.
  • Long-term or repeated use of Pedrox may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Use Pedrox with caution in the elderly; they may be more sensitive to the effects of Pedrox.
  • Use Pedrox with extreme caution in children younger 10 years who have diarrhea or an infection of the stomach or bowel.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pedrox while you are pregnant. Pedrox is found in breast milk. If you are or will be breast-feeding while you use Pedrox, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Nausea, vomiting, indigestion, cramps.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; dark urine; decreased urination; fever, chills, or sore throat; joint pain; red, swollen, or blistered skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; unusual tiredness or weakness; vaginal itching, odor, or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Type Small Molecule
Accession Number DB00778  (APRD01305)
Groups Approved, Investigational, Withdrawn
Synonyms
  • (9e)-Erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)
  • Roxithromycin
  • Roxithromycine
  • Roxithromycinum
  • Roxitromicina
UNII 21KOF230FA
CAS number 80214-83-1
Weight Average: 837.0465
Monoisotopic: 836.524569772
Chemical Formula C41H76N2O15
InChI
InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1
IUPAC Name
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
Protein binding

96%, mainly to alpha1-acid glycoproteins
Toxicity

Most common side-effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting. Less common side-effects include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.
Half life

12 hours

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