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Proctofene (Brand name: Tricor)

  • $0.74
  • Brand name: Tricor
  • Availability: In Stock
  • Active Ingredient Fenofibrate
Proctofene is prescribed to treat patients with high cholesterol and very high levels of triglycerides in the blood.
Other names of Proctofene (Brand name: Tricor): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Apteor   Antilip   Antara   Ab-Vas-F   Adfen-160   Antara   Antilip   Apo Feno Micro   Apo Feno Super   Apo-Feno   Apo-Fenofibrate   Apo-Feno-Micro   Apo-Feno-Super   Arteflex   Atchol-F   Atofast-F   Atorfen   Atormac-TG   Atornet-F   Atorva-TG   Proctofene  
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160 mg
Product name Per Pill Per Pack  
30 pills $1.13 $33.80
60 pills $0.92 $67.59 $55.06
90 pills $0.85 $101.39 $76.32
120 pills $0.81 $135.18 $97.57
180 pills $0.78 $202.77 $140.09
270 pills $0.76 $304.16 $203.88
360 pills $0.74 $405.54 $267.66

Common use

Proctofene contains active substance fenofibrate. In the tissues it turns into the active metabolite: fenofibric acid. In combination with a diet it is used to treat people with very high levels of triglycerides in the blood or lipid disorders. The drug increases activity of lipoprotein lipase, catabolism of triglycerides in the very low density lipoproteins (VLDL), accelerates transfer of cholesterol from atherogenic the very low density lipoproteins (VLDL) to the antiatherogenic high-density lipoproteins (HDL), decreases synthesis of VLDL.

Dosage and direction

Take orally 160 mg of Proctofene three times a day as initial dose to treat high cholesterol levels or a combination of high cholesterol and high triglycerides. For treatment of high triglyceride levels
the starting dose of Proctofene is 54-160 mg a day. It may be gradually increased every 4-8 weeks up to maximal dose of Proctofene 160 mg a day if triglycerides do not improve.

Precautions

Activity of transaminases should be monitored on a regular basis in the patients taking Proctofene. If blood tests for ALT increase 2 and more times and accompaigned by myalgia and muscle weakness, treatment with Proctofene should be discontinued. Proctofene treatment combined with a hypolipidemic diet should be exercised only under control of a doctor and and continue for a long period of time. Proctofene has the potential to cause gallstones.

Contraindications

Hypersensitivity to the components of Proctofene.

Possible side effect

Cholelithiasis, increased levels of transaminases and creatine kinase, nausea, vomiting, diarrhea, myalgia, myositis, rhabdomyolysis (is the rapid breakdown of skeletal muscle due to injury to muscle tissue), acute renal failure, dizziness, headache, abdominal pain, back pain, fatigue, impotence, skin rash. If you experience these symptoms, contact your doctor immediately.

Drug interaction

Inform your doctor about all prescribed and over-the-counter medication you are currently taking and especially about "blood thinners" (warfarin), cyclosporine (cholesterl-lowering drug), MAO inhibitors (selegiline, furazolidone, tranylcypromine, phenelzine, moclobemide), diabetic medicine (glipizide, insulin), estrogens/birth control pills, "statins" (lovastatin, pravastatin, simvastatin, atorvastatin) and high-dose niacin (1 gram or more per day). Combined with Proctofene the two last types of drugs may cause muscle injury (myopathy).

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usual dose next day at the same  time regularly.

Overdose

Any drug taken in excess may be dangerous. If you suspect an overdose, seek immediate medical help.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Chronic indigestion
  • dark urine
  • muscle cramps, pain, stiffness, swelling, or weakness
  • troubled breathing
  • unusual bleeding or bruising
  • unusual tiredness
  • yellow eyes or skin

More Common

  • Runny nose
  • sneezing
  • stuffy nose

Less Common

  • Chills or fever
  • hives, itching, or skin rash
  • muscle aches and pains
  • nausea or vomiting
  • Back pain
  • diarrhea
  • eye irritation
  • gas
  • increased sensitivity of the skin to sunlight

Incidence Not Known

  • Agitation
  • bloating
  • bloody urine
  • decreased frequency or amount of urine
  • lower back or side pain
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • swelling of the face, fingers, or lower legs
  • swollen joints
  • upper right abdominal or stomach pain
  • Lack or loss of strength
Type Small Molecule
Accession Number DB01039  (APRD00405, DB09545)
Groups Approved
Synonyms
  • 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
  • Fenofibrato
  • Fenofibratum
  • Finofibrate
  • FNF
  • Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
  • Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
  • Procetofen
UNII U202363UOS
CAS number 49562-28-9
Weight Average: 360.831
Monoisotopic: 360.112836867
Chemical Formula C20H21ClO4
InChI
InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
IUPAC Name
propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
Protein binding

Serum protein binding is reported to be around 99% [Label].

Toxicity

LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Half life

20 hours

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Algeria, including the following:

  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
  • Tébessa
  • El Oued
  • Skikda
  • Tiaret
  • Béjaïa
  • Tlemcen
  • Ouargla
  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou