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Pih (Brand name: Trandate)

  • $1.08
  • Brand name: Trandate
  • Availability: In Stock
  • Active Ingredient Labetalol
Pih is used for treating high blood pressure.
Other names of Pih (Brand name: Trandate): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Ascool   Albetol   Albetol   Alfabetalol   Ascool   Pih  
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100 mg
Product name Per Pill Per Pack  
30 pills $1.92 $57.68
60 pills $1.45 $115.37 $86.81
90 pills $1.29 $173.05 $115.95
120 pills $1.21 $230.74 $145.08
180 pills $1.13 $346.10 $203.33
270 pills $1.08 $519.16 $290.74

INDICATIONS

Pih is used for treating high blood pressure. It may be used alone or in combination with other medicines, such as diuretics. Pih is an adrenergic receptor blocker. It works by blocking both alpha and beta receptors in the body, which results in the lowering of blood pressure.

INSTRUCTIONS 

Use Pih as directed by your doctor.

  • Take Pih by mouth with or without food.
  • If you miss a dose of Pih, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Pih.

STORAGE

Store Pih at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pih out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Labetalol hydrochloride.

SAFETY INFORMATION

Do NOT use Pih if:

  • you are allergic to any ingredient in Pih
  • you have second- or third-degree heart block, moderate to severe first-degree heart block after a heart attack, heart failure, abnormal heart function test (eg, electrocardiogram [ECG]), or shock caused by serious heart problems
  • you have asthma, obstructive airway disease, or other breathing disorders
  • you have severe slow heartbeat or severe low blood pressure.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Pih. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes, an adrenal gland tumor (pheochromocytoma), lung or breathing problems (eg, bronchitis, emphysema), kidney problems, liver problems, or thyroid problems
  • if you have heart problems (eg, slow heartbeat, irregular heartbeat, Wolff-Parkinson-White syndrome, sick sinus syndrome), low blood pressure, or a history of heart failure, or you have had recent heart attack
  • if you are scheduled to have or have recently had major surgery.

Some medicines may interact with Pih. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Calcium channel blockers (eg, verapamil), cimetidine, or digoxin because they may increase the risk of Pih's side effects
  • General anesthetics (eg, halothane) or nitroglycerin because the risk of their side effects may be increased by Pih
  • Beta-agonists (eg, albuterol) because their effectiveness may be decreased by Pih.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pih may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Pih may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Pih with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Pih may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Do not suddenly stop using Pih without first checking with your doctor. Suddenly stopping Pih may result in chest pain or temporary symptoms such as shaking, sweating, headache, irregular heartbeat, and general unwell feeling. If your doctor decides that you should stop using Pih, your dosage should be reduced over a period of 1 to 2 weeks and you should be carefully monitored.
  • Tell your doctor or dentist that you use Pih before you receive any medical or dental care, emergency care, or surgery.
  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk for an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Pih.
  • Pih may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Pih.
  • If your doctor has instructed you to check your blood pressure and heart rate regularly, be sure to do so.
  • Diabetes patients - Pih may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Diabetes patients - Pih may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including kidney and liver function tests, may be performed while you use Pih. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Pih should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pih while you are pregnant. Pih is found in breast milk. If you are or will be breast-feeding while you use Pih, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Dizziness; indigestion; lightheadedness; nausea; stuffy nose; temporary tingling of the scalp; unusual tiredness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; decreased sexual ability; fever, chills, or persistent sore throat; mental or mood changes; muscle pain or tenderness; persistent loss of appetite; right upper stomach pain; shortness of breath; slow heartbeat; swelling of the hands or feet; unusual bruising or bleeding; vision changes; yellowing of the skin or eyes.
 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • diarrhea
  • increased sweating
  • vomiting

More Common

  • Nausea

Less Common

  • Blurred vision or other changes in vision
  • chills
  • cold sweats
  • confusion
  • difficult or labored breathing
  • dizziness, faintness, or lightheadedness when getting up from lying or sitting position
  • shortness of breath
  • swelling of face, fingers, feet, or lower legs
  • tightness in chest
  • wheezing
  • Acid or sour stomach
  • belching
  • change in taste or bad, unusual, or unpleasant (after) taste
  • decreased interest in sexual intercourse
  • feeling of constant movement of self or surroundings
  • headache
  • heartburn
  • inability to have or keep an erection
  • indigestion
  • lack or loss of strength
  • loss in sexual ability, desire, drive, or performance
  • not able to ejaculate semen
  • rash
  • sensation of spinning
  • stomach discomfort, upset, or pain
  • stuffy nose
Type Small Molecule
Accession Number DB00598  (APRD01062)
Groups Approved
Synonyms
  • 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol
  • 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
  • Labetalol
  • Labetalolum
  • Labetolol
UNII R5H8897N95
CAS number 36894-69-6
Weight Average: 328.4055
Monoisotopic: 328.178692644
Chemical Formula C19H24N2O3
InChI
InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)
IUPAC Name
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide
Protein binding

50%

Toxicity

LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue

Half life

6-8 hours

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Algeria, including the following:

  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
  • Tébessa
  • El Oued
  • Skikda
  • Tiaret
  • Béjaïa
  • Tlemcen
  • Ouargla
  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou