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Ping Ke Ya Xin (Brand name: Micardis)

  • $1.00
  • Brand name: Micardis
  • Availability: In Stock
  • Active Ingredient telmisartan
Ping Ke Ya Xin is used to treat high blood pressure (hypertension) and to reduce the risk of myocardial infarction.
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80 mg
Product name Per Pill Per Pack  
30 pills $2.80 $83.93
60 pills $2.31 $167.85 $138.58
90 pills $2.15 $251.78 $193.24
120 pills $2.07 $335.70 $247.90
180 pills $1.98 $503.55 $357.21
270 pills $1.93 $755.33 $521.18
20 mg
Product name Per Pill Per Pack  
30 pills $1.75 $52.44
60 pills $1.34 $104.88 $80.28
90 pills $1.20 $157.32 $108.13
120 pills $1.13 $209.76 $135.96
180 pills $1.06 $314.64 $191.65
270 pills $1.02 $471.96 $275.16
360 pills $1.00 $629.28 $358.70
40 mg
Product name Per Pill Per Pack  
30 pills $2.49 $74.61
60 pills $1.97 $149.23 $118.30
90 pills $1.80 $223.84 $161.98
120 pills $1.71 $298.45 $205.66
180 pills $1.63 $447.68 $293.02
270 pills $1.57 $671.52 $424.06
360 pills $1.54 $895.36 $555.12

Common use

Ping Ke Ya Xin is used to treat high blood pressure (hypertension) in patients aged 55 years and older to help lower their risk of having certain cardiovascular problems such as stroke, heart attack, or death. Also it is used to reduce the risk of myocardial infarction. It may be used alone or in combination with other antihypertensive agents. Ping Ke Ya Xin lowers blood pressure and improves blood flow. The reduced pressure in the arteries also makes it easier for the heart to pump blood.

Dosage and direction

Take Ping Ke Ya Xin tablets exactly as it is written in prescription of your doctor. Do not change your dose unless your doctor tells you to. Take Ping Ke Ya Xin one time each day at the same time by mouth with or without food. You will get the biggest benefit from this medication if you use it regularly. Also dosage must be individualized. The dosage is based on your medical condition and response to therapy. The usual starting dose of Ping Ke Ya Xin tablets is 40 mg once a day. Blood pressure response is dose-related over the range of 20-80 mg. If you have high blood pressure, it may take 4 weeks before the full benefit of this drug occurs. It is important to continue taking this medication even if you feel good. Most people with high blood pressure do not feel sick.

Precautions

Before you take Ping Ke Ya Xin, tell your doctor if you have liver, kidney or heart problems or any other medical conditions, high blood levels of potassium, severe dehydration (and loss of electrolytes such as sodium), if you are pregnant or are planning to become pregnant, your medical history. Talk with your doctor about the best way to take Ping Ke Ya Xin tablets. Tell your doctor about all the medicines you take: prescription and non-prescription medicines, vitamins, and herbal supplements. Tell your doctor or pharmacist if you are allergic to telmisartan; or to ACE inhibitors (e.g., captopril, lisinopril); or if you have any other allergies. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely because this drug may make you dizzy. Limit alcoholic beverages. You should get up slowly when rising from a seated or lying position. Before having surgery, tell your doctor or dentist that you are taking Ping Ke Ya Xin .

Contraindications

You should not take Ping Ke Ya Xin if you have liver, kidney or heart desease, high blood levels of potassium, if you are pregnant or are planning to become pregnant.

Possible side effects

Ping Ke Ya Xin may cause serious side effects such as injury or death to your unborn baby, low blood pressure (hypotension), swelling of your feet, ankles, face, tongue, throat, or hands, unexplained weight gain, difficulty breathing, sinus pain and congestion (sinusitis), back pain, diarrhea, headache, dizziness, asthenia, coughing, nausea, fatigue, weakness, edema, face edema, lower limb edema, hypersensitivity, erythema, chest pain, atrial fibrillation, congestive heart failure, myocardial infarction, blood pressure increased, hypertension aggravated, hypotension (including postural hypotension), hyperkalemia, syncope, dyspepsia, pain, urinary tract infection, erectile dysfunction, abdominal pain, muscle cramps (including leg cramps). Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects.

Drug interactions

Drug interactions can occur if you take medicines such as diuretics or digoxin with Ping Ke Ya Xin. Some interactions may significantly increase the drug levels in your blood, while others may decrease your blood pressure too much or cause your body to metabolize the medicines differently than intended. Other medicines that may potentially cause Ping Ke Ya Xin drug interactions include potassium-sparing diuretics and potassium supplements. You should talk with your pharmacist or healthcare provider about specific drug interactions with Ping Ke Ya Xin that may apply to you.

Missed dose

If you miss a dose, take it as soon as you remember. If it is close to your next dose, do not take the missed dose. Take the next dose at your regular time.

Overdose

If you take too much Ping Ke Ya Xin, call your doctor, or go to the nearest hospital emergency room right away.

Storage

Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Less Common

  • Abdominal or stomach pain
  • back pain
  • bloating or gas
  • changes in appetite
  • coughing
  • diarrhea
  • dry mouth
  • ear pain or hearing problems
  • fever
  • general tiredness or weakness
  • headache
  • heartburn
  • increased sweating
  • muscle pain or spasm
  • nausea
  • nervousness
  • runny or stuffy nose
  • sneezing
  • sore throat

Incidence Not Known

  • Blurred vision
  • chest pain or discomfort
  • confusion
  • dark-colored urine
  • decreased urine output
  • dilated neck veins
  • extreme fatigue
  • flushing
  • hives or welts
  • hoarseness
  • irregular breathing
  • irritation
  • itching
  • joint pain, stiffness, or swelling
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • muscle cramps or stiffness
  • numbness or tingling in the hands, feet, or lips
  • pain or discomfort in the arms, jaw, back, or neck
  • pounding in the ears
  • rash
  • redness of the skin
  • slow, fast, or irregular heartbeat
  • sweating
  • swelling of the eyelids, face, or lips
  • tightness in the chest
  • trouble breathing or swallowing
  • trouble with speaking or walking
  • trouble with thinking
  • unusual tiredness or weakness
  • unusually warm skin
  • weakness or heaviness of the legs
  • weakness, numbness, or tingling in the arms or legs
  • weight gain
  • Acid or sour stomach
  • belching
  • decreased interest in sexual intercourse
  • difficulty with moving
  • inability to have or keep an erection
  • indigestion
  • joint pain
  • lack or loss of strength
  • leg cramps
  • loss in sexual ability, desire, drive, or performance
  • muscle aching
  • stomach discomfort or upset
  • swelling
  • weakness
Type Small Molecule
Accession Number DB00966  (APRD01247)
Groups Approved, Investigational
Synonyms
  • 4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
  • 4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid
  • 4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid
  • 4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
  • BIBR 277
  • Telmisartan
UNII U5SYW473RQ
CAS number 144701-48-4
Weight Average: 514.6169
Monoisotopic: 514.236876224
Chemical Formula C33H30N4O2
InChI
InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)
IUPAC Name
2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
Protein binding

Highly bound to plasma proteins (>99.5%), mainly albumin and a1-acid glycoprotein. Binding is not dose-dependent.

Toxicity

Intravenous LD50 in rats is 150-200 mg/kg in males and 200 to 250 mg/kg in females. Acute oral toxicity is low: no deaths and no changes occurred in rats or dogs at 2000 mg/kg, the highest dose tested. Limited data are available with regard to overdosage in humans. The most likely manifestations of overdosage with telmisartan would be hypotension, dizziness and tachycardia; bradycardia could occur from parasympathetic (vagal) stimulation.

Half life

Bi-exponential decay kinetics with a terminal elimination half-life of approximately 24 hours.

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Algeria, including the following:

  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
  • Tébessa
  • El Oued
  • Skikda
  • Tiaret
  • Béjaïa
  • Tlemcen
  • Ouargla
  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou