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Pressuril (Brand name: Lisinopril)

  • $0.37
  • Brand name: Lisinopril
  • Availability: In Stock
  • Active Ingredient lisinopril
Pressuril is used to treat high blood pressure (hypertension) in adults and children 6 years old and older.
Analogs of Pressuril (Brand name: Lisinopril): Prinivil   Zestril   Zestoretic  
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Other names of Pressuril (Brand name: Lisinopril): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Axelvin   Asteril   Asrarn   Apo-lisinopril   Amicor   Alapril   Adicanil   Acetan   Acerdil   Acercomp   Acerbon   Acemin   Acelisino comp   Acecomb   Acebitor   Acelisino comp. forte   Acelisino comp. mite   Acelisino comp. semi   Acercomp   Acercomp mite   Acerdil   Acerdil D   Acetan   Acinopril   Adco-Zetomax   Adco-Zetomax CO   Agimlisin   Albigone   Amlace   Amlodac-L   Amlopril   Amlot-L   Amlovas-L   Amtas-LP   Apo-lisinopril   Apo-Lisinopril/HCTZ   Austell-Lisinopril   Acecomb   Acecomb mite   Acecomb semi   Acemin   Acepril   Adicanil   Alapril   Amesos   Amicor   Amicor H   Arrow Lisinopril   Auro-Lisinopril Co   Pressuril  
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10 mg
Product name Per Pill Per Pack  
60 pills $1.14 $68.45
90 pills $0.96 $102.67 $86.65
120 pills $0.87 $136.90 $104.86
180 pills $0.78 $205.34 $141.26
270 pills $0.73 $308.02 $195.89
360 pills $0.70 $410.69 $250.52
2.5 mg
Product name Per Pill Per Pack  
90 pills $0.49 $44.11
180 pills $0.41 $88.22 $74.11
270 pills $0.39 $132.33 $104.09
360 pills $0.37 $176.44 $134.10
5 mg
Product name Per Pill Per Pack  
90 pills $0.70 $63.06
180 pills $0.52 $126.13 $93.33
270 pills $0.46 $189.19 $123.61
360 pills $0.43 $252.25 $153.86

Common use

Pressuril is used to treat high blood pressure (hypertension) in adults and children 6 years and older, including renovascular, acute myocardial infarction in clinically stable condition of the patients, heart failure (adjuvant treatment), diabetic nephropathy. The principle of this drug is to relax blood vessels, causing them to expand, it can lead to prevention of occurrence of strokes, heart attacks and kidney problems. Pressuril is also used after acute myocardial recovery, and is used with other drugs (eg, "water pills" / diuretics, digoxin) to treat heart failure. This drug belongs to a class of medications called ACE inhibitors.

Dosage and direction

Take medicine for adults 1 time a day. The dose is determined individually, depending on the evidence, the state of renal function and concomitant therapy. Typically, the initial dose is 2,5-5 mg, the average maintenance dose - 5-20 mg, the maximum daily - 80 mg.

Precautions

Treatment is carried out under regular medical supervision (water-electrolyte balance). The process of treatment requires monitoring of blood pressure, protein level and plasma potassium, urea nitrogen, creatinine, renal function, blood picture, body weight and dieting. You have to be careful during surgery (including dental), especially when using general anesthetics that have a hypotensive effect.

Contraindications

Hypersensitivity, pregnancy, breast-feeding.

Possible side effects

You can feel headache, dizziness, nervousness, fainting, drowsiness, insomnia, tremors, convulsions, visual disturbances, palpitations, chest pain, hypotension, arrhythmia, dry cough and malignant tumors of the lung, hemoptysis, pain when breathing, bronchitis, dry mouth, indigestion, heartburn, vomiting, diarrhea / constipation, bloating, abdominal pain, renal failure, weakening of libido, impotence, arthritis, neck pain, back pain, rash, urticaria, and syndrome of Stevens - Johnson.

Drug interactions
List of the drugs that can interact with Pressuril: gold injections to treat arthritis, lithium (Lithobid, Eskalith), a potassium supplement such as K-Dur, Klor-Con, salt substitutes that contain potassium, insulin or diabetes medication you take by mouth, aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others, or a diuretic (water pill).

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Pressuril overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.

Storage

Store Pressuril at room temperature away from moisture and heat.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Arm, back, or jaw pain
  • chest discomfort, tightness, or heaviness
  • fast or irregular heartbeat
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • shivering
  • trouble sleeping
  • Acid or sour stomach
  • belching
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • feeling of constant movement of self or surroundings
  • heartburn
  • indigestion
  • muscle cramps
  • sensation of spinning
  • stomach discomfort or upset
  • swelling

More Common

  • Blurred vision
  • cloudy urine
  • confusion
  • decrease in urine output or decrease in urine-concentrating ability
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness

Less Common

  • Abdominal or stomach pain
  • body aches or pain
  • chest pain
  • chills
  • common cold
  • cough
  • diarrhea
  • difficulty breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • nausea
  • runny nose
  • sneezing
  • sore throat
  • vomiting
  • Decreased interest in sexual intercourse
  • inability to have or keep an erection
  • lack or loss of strength
  • loss in sexual ability, desire, drive, or performance
  • rash
Type Small Molecule
Accession Number DB00722  (APRD00560)
Groups Approved, Investigational
Synonyms
  • (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
  • [N2-[(S)-1-CARBOXY-3-phenylpropyl]-L-lysyl-L-proline
  • Lisinopril
  • Lisinopril anhydrous
  • Lisinoprilum
UNII 7Q3P4BS2FD
CAS number 76547-98-3
Weight Average: 405.4879
Monoisotopic: 405.226371117
Chemical Formula C21H31N3O5
InChI
InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
IUPAC Name
(2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid
Protein binding

Lisinopril does not appear to be bound to serum proteins other than ACE.

Toxicity

Symptoms of overdose include severe hypotension, electrolyte disturbances, and renal failure. LD50= 2000 mg/kg(orally in rat). Most frequent adverse effects include headache, dizziness, cough, fatigue and diarrhea.

Half life

Effective half life of accumulation following multiple dosing is 12 hours.

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  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
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  • Skikda
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  • Tlemcen
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  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou