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Phil Pharmawealth/Karnataka Furosemide (Brand name: Lasix)
- $0.25
Asax Apo-furosemida Apix Ansemid Anfuramide Aldalix A Xi Ya Ai Ge Aldactone-D A-Lennon Furosemide Amimide Ansemid Apo Furosemide Apo-Furosemide Aquamide Aquasin Asax Phil Pharmawealth/Karnataka Furosemide
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
90 pills | $0.47 | $41.86 | ||
180 pills | $0.32 | $25.67 | $83.72 $58.05 | |
270 pills | $0.27 | $51.35 | $125.58 $74.22 | |
360 pills | $0.25 | $77.04 | $167.44 $90.40 |
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
60 pills | $0.72 | $43.01 | ||
90 pills | $0.59 | $11.62 | $64.52 $52.90 | |
120 pills | $0.52 | $23.23 | $86.03 $62.80 | |
180 pills | $0.46 | $46.46 | $129.04 $82.58 | |
270 pills | $0.42 | $81.30 | $193.56 $112.27 | |
360 pills | $0.39 | $116.14 | $258.08 $141.95 |
Common use
Furosemide is a loop diuretic causing fast and short diuresis. It possesses natriuretic effect and also decreases levels of Cl- in blood, increases excretion of K+, Ca2+, Mg2+. Penetrating into a renal tubule in ascending thick limb of Henle's loop it blocks re-absorption of Na+ and Cl-. Due to increased excretion of Na+ secondary intensified excretion of water occurs and as well as increased secretion of K+ in distal part of the renal tubule. Simultaneously excretion of Ca2+ and Mg2+ increases. Furosemide is used to treat edema syndrome in patients with chronic heart failure (degree II and III), cirrhosis, diseases of kidneys, acute heart failure (pulmonary edema), brain edema, hypertensive crisis, arterial hypertension and others.
Dosage and direction
Take exactly as it was prescribed by your doctor.
Precautions
Before using Furosemide, consult your doctor if you suffer from kidney disease, liver disease, gout, lupus, diabetes, or an allergy to sulfa drugs. Avoid becoming dehydrated as Furosemide makes you urinate more often. Do not stop taking the drug even if you feel fine as high blood pressure often has no symptoms. Avoid taking the drug if you are pregnant or breastfeeding.
Contraindications
Hypersensitivity, acute kidney failure with anuria, severe liver failure, liver coma and precoma, stenois of urethra, acute glomerulonephritis, urinary tract obstruction, precoma, hyperglycemic coma, gout, arterial hypotension, heart attack, pancreatitis and others.
Possible side effect
Contact your physician for medical attention if you have signs of allergy or any of the following conditions: dry mouth, thirst, nausea, vomiting; weakness, drowsiness, restless, or light-headed, fast or uneven heartbeat, muscle pain, less than usual urination or absence of urination, easy bruising or bleeding, red blistering skin rash, hair loss.
Drug interaction
Hearing damage may occur if Furosemide is administered with aminoglycoside antibiotics (gentamicin and others) or Edecrin - another diuretic. Concomitant use of Furosemide and aspirin may cause high blood levels of aspirin and aspirin toxicity. Furosemide is able to reduce excretion of lithium by the kidneys. Sucralfate (Carafate) reduces the action of Furosemide. Intake of Ingestion of Furosemide and Sucralfate should be separated by two hours.
Missed dose
The medication is sometimes administered for single use so you will not need a dosing schedule. If you take Furosemide regularly and forgot to take a dose, take it as soon as you remember. Skip the missed dose if it is almost time for the next intake. Resume your regular schedule. Do not compensate the missed dose by taking an extra one.
Overdose
In case of loss of appetite, ringing in ears, severe weakness, dizziness, confusion, lightheadedness, or fainting, seek for immediate doctor's attention.
Storage
Keep away from children at room temperature in a dry and dark place.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:
Rare
- Chest pain
- chills
- cough or hoarseness
- fever
- general feeling of tiredness or weakness
- headache
- lower back or side pain
- painful or difficult urination
- shortness of breath
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swollen or painful glands
- tightness in the chest
- unusual bleeding or bruising
- unusual tiredness or weakness
- wheezing
Incidence Not Known
- Back or leg pains
- black, tarry stools
- bleeding gums
- blistering, peeling, or loosening of the skin
- bloating
- blood in the urine or stools
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- changes in skin color, pain, tenderness, or swelling of the foot or leg
- clay-colored stools
- cloudy urine
- cold sweats
- confusion
- constipation
- continuing ringing or buzzing or other unexplained noise in the ears
- coughing up blood
- cracks in the skin
- darkened urine
- diarrhea
- difficulty breathing
- dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
- dry mouth
- fast heartbeat
- flushed, dry skin
- fruit-like breath odor
- greatly decreased frequency of urination or amount of urine
- hearing loss
- increased hunger
- increased thirst
- indigestion
- itching
- loss of appetite
- nausea or vomiting
- nosebleeds
- pain in the joints or muscles
- pains in the stomach, side, or abdomen, possibly radiating to the back
- pale skin
- pinpoint red spots on the skin
- red, irritated eyes
- red, swollen skin
- skin rash
- spots on your skin resembling a blister or pimple
- sweating
- swelling of the feet or lower legs
- trouble breathing with exertion
- unusual weight loss
- vomiting of blood
- yellow eyes or skin
- Feeling of constant movement of self or surroundings
- hives or welts
- increased sensitivity of the skin to sunlight
- muscle spasm
- redness or other discoloration of the skin
- restlessness
- sensation of spinning
- severe sunburn
- weakness
Type | Small Molecule |
Accession Number | DB00695 (APRD00608, DB07799) |
Groups | Approved, Vet approved |
Synonyms |
|
UNII | 7LXU5N7ZO5 |
CAS number | 54-31-9 |
Weight | Average: 330.744 Monoisotopic: 330.007719869 |
Chemical Formula | C12H11ClN2O5S |
InChI | InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19) |
IUPAC Name | 4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid |
Protein binding | 95% bound to plasma proteins |
Toxicity | Profound diuresis may cause fluid and electrolyte depletion. Excessive dehydration and potassium depletion may occur. Excessive diuresis may cause rapid weight loss, orthostatic hypotension or acute hypotensive episodes. May also cause tinnitus, reversible or permanent hearing loss or reversible deafness. |
Half life | 2 hours |
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