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PMS-Colchicine (Brand name: Colchicine)

  • $0.51
  • Brand name: Colchicine
  • Availability: In Stock
  • Active Ingredient
PMS-Colchicine is used for treating and preventing pain associated with gouty arthritis.
Other names of PMS-Colchicine (Brand name: Colchicine): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
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0.5 mg
Product name Per Pill Per Pack  
60 pills $0.79 $47.40
90 pills $0.68 $71.10 $61.15
120 pills $0.62 $94.80 $74.89
180 pills $0.57 $142.20 $102.38
270 pills $0.53 $213.30 $143.61
360 pills $0.51 $284.40 $184.86

Drug Uses

PMS-Colchicine is used for treating and preventing pain associated with gouty arthritis. It may also be used for other conditions as determined by your doctor.

How to use

Use PMS-Colchicine as directed by your doctor.

Take PMS-Colchicine by mouth with or without food.
Do not eat grapefruit or drink grapefruit juice while you use PMS-Colchicine.
Ask your health care provider any questions you may have about how to use PMS-Colchicine.
Drug Class and Mechanism

PMS-Colchicine is an anti-gout agent. It works by decreasing inflammation.

Missed Dose

If you miss a dose of PMS-Colchicine and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store PMS-Colchicine at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep PMS-Colchicine out of the reach of children and away from pets.

Warnings/Precautions

Do not use PMS-Colchicine if:

you are allergic to any ingredient in PMS-Colchicine;
Contact your doctor or health care provider right away if any of these apply to you.

Important :
Do not drink alcohol or use medicines that may cause drowsiness (e.g., sleep aids, muscle relaxers) while you are using PMS-Colchicine ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
PMS-Colchicine may cause false-positive results when testing urine for blood or hemoglobin.
If you are taking PMS-Colchicine to treat a painful attack of gouty arthritis and you experience nausea, vomiting, or diarrhea, stop taking PMS-Colchicine , even if pain continues, unless your doctor directs otherwise.
Lab tests may be performed while you use PMS-Colchicine . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Pregnancy and breast-feeding: PMS-Colchicine has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using PMS-Colchicine while you are pregnant. PMS-Colchicine is found in breast milk. If you are or will be breast-feeding while you use PMS-Colchicine , check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

diarrhea; nausea; stomach pain; vomiting.
Seek medical attention right away if any of these severe side effects occur:
severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; infection; numbness or tingling; severe diarrhea; sore throat; tiredness; unusual bleeding or bruising; weakness.

More Information

PMS-Colchicine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Black, tarry stools
  • blood in the urine or stools
  • burning, "crawling", or tingling feeling in the skin
  • difficulty with breathing when exercising
  • fever with or without chills
  • headache
  • large, hive-like swellings on the face, eyelids, mouth, lips, or tongue
  • muscle weakness
  • numbness in the fingers or toes (usually mild)
  • pain
  • peeling of the skin
  • pinpoint red spots on the skin
  • redness
  • skin rash or hives
  • sores, ulcers, or white spots on the lips or in the mouth
  • sore throat
  • swelling
  • tenderness
  • unusual bleeding or bruising
  • unusual tiredness or weakness

More Common

  • Diarrhea
  • nausea or vomiting
  • stomach pain

Less Common

  • Hair loss
  • loss of appetite
Type Small Molecule
Accession Number DB01394
Groups Approved
Synonyms
  • Colchicin
  • Colchicina
  • Colchicinum
UNII SML2Y3J35T
CAS number 64-86-8
Weight Average: 399.437
Monoisotopic: 399.168187537
Chemical Formula C22H25NO6
InChI
InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
IUPAC Name
N-{3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0²,⁷]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl}acetamide
Protein binding

Low to moderate (30 to 50%).

Toxicity

The onset of toxic effects is usually delayed for several hours or more after the ingestion of an acute overdose. Nausea, vomiting, abdominal pain, and diarrhea occur first. The diarrhea may be bloody due to hemorrhagic gastroenteritis. Burning sensations of the throat, stomach, and skin may be prominent symptoms. Extensive vascular damage may result in shock. Kidney damage, evidenced by hematuria and oliguria, may occur. Muscular weakness may be marked, and ascending paralysis of the central nervous system may develop; the patient usually remains conscious. Delirium and convulsions may occur. Death due to respiratory arrest may result. Although death from the ingestion of as little as 7 mg has been reported, much larger doses have been survived .

Half life

Elimination half-life is approximately 1 hour in healthy subjects, although a study with an extended sampling time reported mean terminal elimination half-life values of approximately 9 to 10.5 hours. Other studies have reported half-life values of approximately 2 hours in patients with alcoholic cirrhosis and approximately 2.5 hours in patients with familial Mediterranean fever.

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Algeria, including the following:

  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
  • Tébessa
  • El Oued
  • Skikda
  • Tiaret
  • Béjaïa
  • Tlemcen
  • Ouargla
  • Béchar
  • Mostaganem
  • Bordj Bou Arréridj
  • Chlef
  • Souk Ahras
  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou