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Pretir (Brand name: Zithromax)
- $0.40
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Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
30 pills | $2.44 | $73.10 | ||
60 pills | $1.64 | $47.85 | $146.21 $98.36 | |
90 pills | $1.37 | $95.71 | $219.31 $123.61 | |
120 pills | $1.24 | $143.56 | $292.42 $148.86 | |
180 pills | $1.11 | $239.26 | $438.62 $199.37 | |
270 pills | $1.02 | $382.81 | $657.94 $275.13 | |
360 pills | $0.97 | $526.36 | $877.25 $350.89 |
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
30 pills | $1.55 | $46.35 | ||
60 pills | $1.12 | $25.28 | $92.71 $67.42 | |
90 pills | $0.98 | $50.57 | $139.06 $88.49 | |
120 pills | $0.91 | $75.85 | $185.41 $109.56 | |
180 pills | $0.84 | $126.41 | $278.12 $151.70 | |
270 pills | $0.80 | $202.26 | $417.18 $214.92 | |
360 pills | $0.77 | $278.14 | $556.24 $278.10 |
Product name | Per Pill | Savings | Per Pack | |
---|---|---|---|---|
60 pills | $0.72 | $43.32 | ||
90 pills | $0.59 | $11.70 | $64.98 $53.28 | |
120 pills | $0.53 | $23.39 | $86.64 $63.25 | |
180 pills | $0.46 | $46.78 | $129.96 $83.18 | |
270 pills | $0.42 | $81.86 | $194.94 $113.08 | |
360 pills | $0.40 | $116.96 | $259.92 $142.96 |
Product Description
Common use
Pretir is a semi-synthetic macrolide antibiotic chemically related to erythromycin which is effective against majority of species of gram positive and gram negative microorganisms such as genus Staphylococcus; S. aureus, S. pneumoiane, S. pyogenes, S. agalactiae, Haemophilus influenzae and parainfluenzae, Moraxela catarrhalis, Bacteroides fragilis, Escherichia coli, Bordetella ssp., Borrelia burgdorferi, Haemophilus ducreui, Nisseria gonorrhoeae Ø Chlamidia trachomati. In vitro it showed activity against Legionella pneumophila, Mycoplasma pneumoia Ø hominis, Helicobacter pylori, Toxoplasma gondii, Ureaplasma urealiticum. As a Macrolide antibiotic Pretir inhibits bacterial protein synthesis and prevents bacteria from growth and propagation. It is used to treat infections of upper and low respiratory organs (tonsillitis, otitis, sinusitis, pneumonia), urogenital infections (urethritis, prostatitis, cervicitis, adnexitis caused by chlamydia, gonorrhea, early syphilis), intestinal infections, ulcer of stomach and duodenum.
Dosage and directions
Take exactly as prescribed and do not discontinue your treatment even if you feel fine and your symptoms improved without your doctor's permission. Take Pretir tablet with a big glass of water. To prepare a liquid suspension form one dose packet mix one packet with 2 ounces of water, shake and drink at once. Do not use the suspension which was prepared longer than 12 hours ago. Tablets and suspension can be taken with or without food while capsules should be taken on an empty stomach 2 hours before or after a meal.
Precautions
There are no evidences if Pretir affects an unborn baby or excretes in a breast milk. This medication should be used by pregnant and breastfeeding women only if expected benefit prevails over potential risk for the baby.
Contraindications
Hypersensitivity to Pretir and related drugs such as azithromycin or erythromycin.
Possible side effect
Among side effects may be diarrhea or loose stools, nausea, abdominal pain, and vomiting, uneven heartbeats, loss of appetite, dark urine, clay-colored stools, jaundice, fever, rash, red skin, headache. You should call your doctor and inform about such symptoms or get immediate medical attention.
Drug interaction
Pretir is not recommended to take with aluminum- or magnesium- based antacids, such as Mylanta or Maalox as they decrease its absorption in the intestine.
Missed dose
Take the missed dose when you remember. If it is almost time of the next intake just skip it and return to your schedule.
Overdose
Symptoms of overdose may appear as nausea, vomiting, diarrhea, and stomach discomfort. In this case look for immediate medical attention.
Storage
Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:
Rare
- Blistering, burning, crusting, dryness, or flaking of the skin
- blurred vision
- cough
- decreased vision
- discharge from the eye
- fever
- headache
- hives or welts
- itching, scaling, severe redness, soreness, or swelling of the skin
- pain or tenderness around the eyes and cheekbones
- painful irritation of the clear front part of the eye
- shortness of breath or troubled breathing
- skin rash
- stuffy or runny nose
- swelling of the face
- swelling or puffiness of the eyes
- tightness of the chest or wheezing
- Change in taste
- dry eyes
- loss of taste
Less Common
- Burning, redness, stinging, or other eye irritation
Type | Small Molecule |
Accession Number | DB00207 (APRD00397) |
Groups | Approved |
Synonyms |
|
UNII | J2KLZ20U1M |
CAS number | 83905-01-5 |
Weight | Average: 748.9845 Monoisotopic: 748.508525778 |
Chemical Formula | C38H72N2O12 |
InChI | InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
IUPAC Name | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one |
Protein binding | Serum protein binding is variable in the concentration range approximating human exposure, decreasing from 51% at 0.02 µg/mL to 7% at 2 µg/mL. |
Toxicity | Potentially serious side effects of angioedema and cholestatic jaundice were reported |
Half life | 68 hours |
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- Algiers
- Oran
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