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- Genuine branded medication
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Panalene Clin (Brand name: Cleocin)
- $2.03
Arfarel Antirobe Aniclindan Anerocid Albiotin Aknezel k Aknet Agis Acnestop Acnatac Acneklin Acneris Acneris-AD Acnesol Acnestar Acnovate Adgraze-AC Aknet Alfaclindamycin Anich Arfarel Aviclin Axcel Clindamycin Acanya Acnestop Acnex Acnin Adacin Aktufoam Aledo Ao Li Xian Abanxl-300 Acneal Acnocin Albiotin Anerocid Aniclindan Antirobe Panalene Clin
| Product name | Per Pill | Savings | Per Pack | |
|---|---|---|---|---|
| 30 pills | $3.07 | $92.13 | ||
| 60 pills | $2.44 | $37.59 | $184.25 $146.66 | |
| 90 pills | $2.24 | $75.18 | $276.38 $201.20 | |
| 120 pills | $2.13 | $112.76 | $368.51 $255.74 | |
| 180 pills | $2.03 | $187.94 | $552.76 $364.82 |
Product Description
Common use
Panalene Clin kills sensitive bacteria by stopping the production of essential bacterial proteins after binding a bacterial ribosome. Panalene Clin is close by its qualities to Lincomycin. Lincosamides are usually used to treat staphylococci and streptococci. Panalene Clin is administered to treat protozoal diseases such as malaria, infections of respiratory system, skin and soft tissures, bones and joints, abdominal organs, and others. It does not treat meningitis.
Dosage and directions
Take orally four times a day with or without food with a full glass of water. Take Panalene Clin at evenly spaced intervals.
Precautions
This medication should be used only for treatment of serious bacterial infections due to its ability to cause severe and even fatal intestinal condition known as pseudomembranous colitis. This condition may appear during treatment or even weeks after treatment has stopped. So if you have persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool do not use anti-diarrhea drugs and inform your doctor about your condition.
Contraindications
Do not take this drug if you have antibiotic-associated colitis, Crohn disease, ulcerative colitis or meningitis, have allergy to Panalene Clin or Lincomycides. Inform your doctor if you are pregnant or breastfeeding, if you have diarrhea, a history of liver problems or stomach or bowel problems before taking this medication.
Possible side effect
Mild diarrhea, nausea, vomiting or upset stomach may occur. If they persist or become bothersome contact your doctor. Seek medical attention right away if you have serious signs of allergy (hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face) or other side effects: bloody or tarry stools, decreased urination, severe stomach cramps or pain, unusual vaginal discharge, yellowing of the skin or eyes.
Drug interaction
Inform your doctor about all drugs you are taking and especially about erythromycin, kaolin-pectin, live bacterial vaccines. Clindamycin may increase the effects of drugs used during surgery so your doctor should know if you are taking Panalene Clin and plan to be operated.
Missed dose
Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.
Overdose
Panalene Clin overdose may cause serious consequences, so in case of persistent symptoms of abdominal pain, nausea, vomiting, and diarrhea contact your doctor.
Storage
Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:
Rare
- Cracks in the skin
- loss of heat from the body
- red, swollen skin scaly skin
Incidence Not Known
- Abdominal or stomach cramps, pain, or tenderness
- black, tarry stools
- bleeding gums
- blistering, peeling, or loosening of the skin
- bloating
- blood in the urine or stools
- blurred vision
- chest pain
- chills
- clay-colored stools
- cloudy urine
- confusion
- cough or hoarseness
- dark urine
- decrease in the amount of urine
- diarrhea
- diarrhea, watery and severe, which may also be bloody
- difficulty with swallowing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- fast heartbeat
- fever with or without chills
- general feeling of tiredness or weakness
- headache
- heartburn
- heart stops
- hives or welts, itching, or skin rash
- increased thirst
- itching of the vagina or genital area
- joint or muscle pain
- loss of appetite
- lower back or side pain
- nausea or vomiting
- no breathing
- no pulse or blood pressure
- pain during sexual intercourse
- pain in the lower back or side
- painful or difficult urination
- pinpoint red spots on the skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rash with flat lesions or small raised lesions on the skin
- red skin lesions, often with a purple center
- red, irritated eyes
- redness of the skin
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- swollen glands
- thick, white vaginal discharge with no odor or with a mild odor
- thirst
- tightness in the chest
- trouble breathing
- unconscious
- unpleasant breath odor
- unusual bleeding or bruising
- unusual tiredness or weakness
- unusual weight loss
- vomiting of blood
- yellow eyes or skin
| Type | Small Molecule |
| Accession Number | DB01190 (APRD00566) |
| Groups | Approved, Vet approved |
| Synonyms |
|
| UNII | 3U02EL437C |
| CAS number | 18323-44-9 |
| Weight | Average: 424.983 Monoisotopic: 424.179870573 |
| Chemical Formula | C18H33ClN2O5S |
| InChI | InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1 |
| IUPAC Name | (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboximidic acid |
| Protein binding | 92-94% |
| Toxicity | Adverse effects include nausea (may be dose-limiting), diarrhea, pseudomembranous colitis, allergic reactions, hepatoxicity, transient neutropenia and eosinophilia and agranulocytosis. Pseudomembranous colitis occurs in 0.01 - 10% of patients and occurs more commonly than with other antibiotics. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin. |
| Half life | 2.4 hours |
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