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Pharex chloramphenicol (Brand name: Chloramphenicol)
Atralfenicol Asclor Aristophen Arifenicol Aquapred Anuar Antibioptal Anacetin Amplobiotic Amphicol Alphagram Alfa cloromicol Abefen Acromaxfenicol Adcocetine 1% Agophenol Alfa cloromicol Alphagram Amicol Oogzalf Amphicol-V Anacetin Andrecin Antibioptal A-Phenicol A-phenicol D Aristophen Armacort Anpheclor Pharex chloramphenicol
|Product name||Per Pill||Savings||Per Pack|
|60 pills||$0.94||$15.82||$72.50 $56.68|
|90 pills||$0.86||$31.64||$108.76 $77.12|
|120 pills||$0.81||$47.46||$145.01 $97.55|
|180 pills||$0.77||$79.09||$217.51 $138.42|
|270 pills||$0.74||$126.55||$326.27 $199.72|
|360 pills||$0.73||$174.02||$435.02 $261.00|
|Product name||Per Pill||Savings||Per Pack|
|90 pills||$0.68||$13.01||$73.87 $60.87|
|120 pills||$0.60||$26.00||$98.50 $72.49|
|180 pills||$0.53||$52.00||$147.74 $95.74|
|270 pills||$0.48||$91.02||$221.62 $130.60|
|360 pills||$0.46||$130.03||$295.49 $165.46|
Pharex chloramphenicol is used for treating serious infections caused by certain bacteria. Pharex chloramphenicol is an antibiotic. It works by killing or slowing the growth of sensitive bacteria.
Use Pharex chloramphenicol as directed by your doctor.
- Take Pharex chloramphenicol by mouth with or without food.
- If you miss a dose of Pharex chloramphenicol, use it as soon as possible. Then use your doses at evenly spaced times as directed by your doctor. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Pharex chloramphenicol.
Store Pharex chloramphenicol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Pharex chloramphenicol out of the reach of children and away from pets.
Do NOT use Pharex chloramphenicol if:
- you are allergic to any ingredient in Pharex chloramphenicol
- you have previously had serious side effects from Pharex chloramphenicol
- you have a low white or red blood cell count or decreased blood platelets
- you have a minor infection such as a cold, flu, throat infection, or you are using Pharex chloramphenicol to prevent a bacterial infection
- you are taking other medicines that may decrease your bone marrow (eg, cancer chemotherapy); check with your doctor or pharmacist if you are unsure if any of your other medicines may decrease your bone marrow.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Pharex chloramphenicol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have anemia, bone marrow problems, liver disease, or kidney problems.
Some medicines may interact with Pharex chloramphenicol. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin) because side effects, including risk of bleeding, may be increased
- Hydantoins (eg, phenytoin) or sulfonylureas (eg, glyburide) because the actions and side effects of these medicines may be increased.
- Medicines that may decrease your bone marrow (eg, cancer chemotherapy ) because the risk of serious side effects, such as low blood platelet levels and low white blood cell counts, may be increased; check with your doctor or pharmacist if you are unsure if any of your medicines may decrease your bone marrow.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Pharex chloramphenicol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Do not exceed the recommended dose or use Pharex chloramphenicol for longer than prescribed without checking with your doctor.
- Pharex chloramphenicol is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
- It is important to use Pharex chloramphenicol for the full course of treatment. Failure to do so may decrease the effectiveness of Pharex chloramphenicol and increase the risk that the bacteria will no longer be sensitive to Pharex chloramphenicol and will not be able to be treated by this or certain other antibiotics in the future.
- Long-term or repeated use of Pharex chloramphenicol may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
- If symptoms of "gray syndrome" (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature) occur in a newborn or infant, contact your doctor. Death may occur within hours of the onset of symptoms. Stopping use of Pharex chloramphenicol when symptoms first appear increases the chance for a complete recovery.
- Pharex chloramphenicol may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.
- Pharex chloramphenicol may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
- Diabetes patients - Pharex chloramphenicol may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
- LAB TESTS, including complete blood cell counts, may be performed to monitor your progress or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Pharex chloramphenicol with extreme caution in children younger 1 year. Safety and effectiveness in this age group have not been confirmed.
- Use Pharex chloramphenicol with extreme caution in children younger 10 years who have diarrhea or a stomach or bowel infection.
- Use Pharex chloramphenicol with extreme caution in premature and full-term infants because they may be more sensitive to the effects of Pharex chloramphenicol, especially the risk of "gray syndrome."
- Pregnancy and breast-feeding: If you become pregnant while taking Pharex chloramphenicol, discuss with your doctor the benefits and risks of using Pharex chloramphenicol during pregnancy. Pharex chloramphenicol should be used with extreme caution during full-term pregnancy and labor because the fetus may experience severe side effects. Pharex chloramphenicol is excreted in breast milk. Do not breastfeed while taking Pharex chloramphenicol.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Mild diarrhea, nausea, or vomiting.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; dark urine; delirium; depression; headache; fever, chills, or sore throat; pain, redness, or swelling at the injection site; symptoms of "gray syndrome" in an infant (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature); unusual bleeding or bruising; unusual tiredness; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.
Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:
- Itching, redness, skin rash, swelling, or other sign of irritation not present before use of this medicine
- Burning or stinging
|Accession Number||DB00446 (APRD00862, EXPT00942)|
|Groups||Approved, Vet approved|
Plasma protein binding is 50-60% in adults and 32% is premature neonates.
Oral, mouse: LD50 = 1500 mg/kg; Oral, rat: LD50 = 2500 mg/kg. Toxic reactions including fatalities have occurred in the premature and newborn; the signs and symptoms associated with these reactions have been referred to as the gray syndrome. Symptoms include (in order of appearance) abdominal distension with or without emesis, progressive pallid cyanosis, vasomotor collapse frequently accompanied by irregular respiration, and death within a few hours of onset of these symptoms.
Half-life in adults with normal hepatic and renal function is 1.5 - 3.5 hours. In patients with impaired renal function half-life is 3 - 4 hours. In patients with severely impaired hepatic function half-life is 4.6 - 11.6 hours. Half-life in children 1 month to 16 years old is 3 - 6.5 hours, while half-life in infants 1 to 2 days old is 24 hours or longer and is highly variable, especially in low birth-weight infants.
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