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Paferxin (Brand name: Cephalexin)

  • $1.32
  • Brand name: Cephalexin
  • Availability: In Stock
  • Active Ingredient cephalexin
Paferxin is a cephalosporin antibiotic used in the treatment of respiratory infections and ear infections.
Analogs of Paferxin (Brand name: Cephalexin): Keflex   Keftab  
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Other names of Paferxin (Brand name: Cephalexin): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Avloxin   Aurocef   Aristocef   Anxer   Alsporin   Alexin   Alexcef   Aescephaline   Acrocep   Paferxin  
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500 mg
Product name Per Pill Per Pack  
30 pills $1.85 $55.45
60 pills $1.37 $110.90 $82.47
90 pills $1.22 $166.35 $109.49
120 pills $1.14 $221.80 $136.51
180 pills $1.06 $332.69 $190.55
270 pills $1.01 $499.04 $271.59
360 pills $0.98 $665.39 $352.66
250 mg
Product name Per Pill Per Pack  
30 pills $1.39 $41.81
60 pills $1.08 $83.61 $64.55
90 pills $0.97 $125.42 $87.28
120 pills $0.92 $167.22 $110.03
180 pills $0.86 $250.83 $155.50
270 pills $0.83 $376.25 $223.72
360 pills $0.81 $501.66 $291.96

Product Description

Common use

Paferxin is attributed as antibiotic of cephalosporins group which acts against bacteria preventing formation of their cell walls. It is enough resistant to penicillinases of gram positive microorganisms but can be destroyed by beta-lactamases of gram negative ones. It shows broad spectrum activity against gram positive microorganisms such as Staphylococcus, Staphylococcus epidermidis; Streptococcus, Corynebacterium diphtheriae, Clostridium, Actinomyces israelii, Bacillus anthracis, gram negative microorganisms like Escherichia coli, Klebsiella, Proteus mirabilis, Neisseria gonorrhoeae, Neisseria meningitidis, Shigella, Salmonella. Common infections that are treated with Paferxin include infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis) and pneumonia as well as in urinary tract, skin, and bones.

Dosage and directions

The dose of Paferxin for adults is 1 to 4 grams in divided doses. The interval between doses may be 6 or 12 hours depending on the infection.

Precautions

Before using Paferxin, tell your doctor if you are allergic to any drugs (especially penicillins), have kidney or liver disease, a stomach or intestinal disorder such as colitis, and diabetes.

Contraindications

Hypersensitivity to Paferxin, cephalosporins (Ceclor, Duricef, Omnicef, Spectracef, Suprax, Cefzil, Fortaz, Ceftin) and beta-lactamase antibiotics. Cautiousness should be exercised in patients with kidney disorder, pseudomembranous colitis, pregnancy, breastfeeding and babies younger than 6 month.

Possible side effect

Most common side effects may include signs of allergy (hives, rash, swelling of face and tongue), seizure, fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, pale or yellowed skin, dark colored urine, fever, hallucinations, confusion or weakness, easy bruising or bleeding, unusual weakness, confusion, agitation, decreased or absent urination. In case of serious and persistent side effects listed above seek immediate medical help.

Drug interaction

Inform your doctor about all medications you take and especially about live vaccines, probenecid. Paferxin may decrease the effectiveness of combination-type contraceptive pills. This medication is able to show false positive results with certain diabetic urine testing products. Paferxin increases effects of indirect anticoagulants, polphenilbutazone, furocemide. Salicylates and indomethacin slow excretion of cephalolexin by kidneys. Medications decreasing secretion in renal tubules increase concentration of the medication blood serum and slow down its excretion.

Missed dose

If you missed a dose take it as soon as you remember. If it is almost time of your next dose just skip it and return to your regular schedule. Never double the dose of this medication.

Overdose

In case of serious and persistent symptoms of nausea, vomiting, stomach pain, diarrhea, and blood in your urine consult your doctor about medical attention.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Contact the support team to get instructions from qualified doctors as taking the treatment in accordance with the safety recommendations and instructions is halfway to a flawless and successful treatment course. Patients, who are hypersensitive to any ingredients of the remedy should avoid its use. The following mild to severe abnormalities can bother patients, who misuse or overuse the drug:

Rare

  • Abdominal or stomach pain
  • blistering, peeling, or loosening of the skin
  • chills
  • clay-colored stools
  • cough
  • dark urine
  • diarrhea
  • dizziness
  • fever
  • general tiredness and weakness
  • headache
  • itching or rash
  • joint or muscle pain
  • light-colored stools
  • loss of appetite
  • nausea and vomiting
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • unpleasant breath odor
  • unusual tiredness or weakness
  • upper right abdominal or stomach pain
  • vomiting of blood
  • yellow eyes or skin

More Common

  • Diarrhea

Incidence Not Known

  • Abdominal or stomach cramps or tenderness
  • back or leg pains
  • black, tarry stools
  • bleeding gums
  • bloating
  • blood in the urine or stools
  • chest pain
  • coughing up blood
  • diarrhea, watery and severe, which may also be bloody
  • difficulty with breathing or swallowing
  • fast heartbeat
  • general body swelling
  • hives
  • increased menstrual flow or vaginal bleeding
  • increased thirst
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • nosebleeds
  • pain
  • painful or difficult urination
  • pale skin
  • paralysis
  • pinpoint red spots on the skin
  • prolonged bleeding from cuts
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red or black, tarry stools
  • red or dark brown urine
  • swollen or painful glands
  • tightness in the chest
  • unusual bleeding or bruising
  • unusual weight loss
  • watery or bloody diarrhea
  • Acid or sour stomach
  • anxiety
  • belching
  • burning feeling in the chest or stomach
  • difficulty with moving
  • dry mouth
  • heartburn
  • hyperventilation
  • indigestion
  • irregular heartbeats
  • irritability
  • itching of the vagina or genital area
  • muscle pain or stiffness
  • nervousness
  • pain during sexual intercourse
  • pain, swelling, or redness in the joints
  • redness of the skin
  • restlessness
  • seeing, hearing, or feeling things that are not there
  • shaking
  • stomach upset
  • trouble sleeping
  • white or brownish vaginal discharge
Type Small Molecule
Accession Number DB00567  (APRD00250)
Groups Approved, Investigational, Vet approved
Synonyms
  • (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
  • 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
  • Anhydrous cefalexin
  • Anhydrous cephalexin
  • Cefalexin
  • Cefalexin anhydrous
  • Cefalexina
  • Céfalexine
  • Cefalexinum
  • Cephalexin anhydrous
UNII 5SFF1W6677
CAS number 15686-71-2
Weight Average: 347.389
Monoisotopic: 347.093976737
Chemical Formula C16H17N3O4S
InChI
InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
IUPAC Name
(6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Protein binding

14%

Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. The oral median lethal dose of cephalexin in rats is >5000 mg/kg.

Half life

1 hour

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  • Algiers
  • Oran
  • Constantine
  • Annaba
  • Blida
  • Batna
  • Djelfa
  • Sétif
  • Sidi Bel Abbès
  • Biskra
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  • El Oued
  • Skikda
  • Tiaret
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  • Tlemcen
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  • Bordj Bou Arréridj
  • Chlef
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  • Médéa
  • El Eulma
  • Touggourt
  • Ghardaïa
  • Saïda
  • Laghouat
  • M'Sila
  • Jijel
  • Relizane
  • Guelma
  • Aïn Béïda
  • Khenchela
  • Bousaada
  • Mascara
  • Tindouf
  • Tizi Ouzou